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Diseases of arteries, arterioles and capillaries

DOID EFO MESH SNOMED PheWeb

I9_DOAAC

vascular disease: A non-neoplastic or neoplastic disorder affecting the arteries, veins, or lymphatic vessels. Examples include vasculitis, thrombophlebitis, arteriosclerosis, lymphedema, hemangioma, and angiosarcoma.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 I70-I79
Cause of death: ICD-10 I70-I79

21928

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

21928

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Check minimum number of events None

21928

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Include endpoints

25309

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I9_DOAAC

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 25309 8203 17106
Unadjusted prevalence (%) 7.11 4.13 10.87
Mean age at first event (years) 64.61 61.37 66.16

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.61 [4.12, 5.15] <1e-100 8064
15 years 0.02 2.37 [2.15, 2.61] 1.1e-67 3125
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_DOAAC – Diseases of arteries, arterioles and capillaries
GWS hits:

Survival analyses between endpoints

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Plot

before Diseases of arteries, arterioles and capillaries
after Diseases of arteries, arterioles and capillaries

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Drugs most likely to be purchased after Diseases of arteries, arterioles and capillaries

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