ILD differential diagnosis

ILD_DIFF_DG

interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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ILD_DIFF_DG

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 153305 80816 72489
Unadjusted prevalence (%) 43.09 40.73 46.06
Mean age at first event (years) 48.05 43.91 52.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 5.87 [5.51, 6.26] <1e-100 23850
15 years 0.01 3.21 [2.99, 3.45] <1e-100 7455
5 years 0.01 7.02 [6.57, 7.51] <1e-100 6644
1 year 0.01 33.15 [29.69, 37.01] <1e-100 7378

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ILD_DIFF_DG – ILD differential diagnosis
GWS hits:

Survival analyses between endpoints

Plot

before ILD differential diagnosis
after ILD differential diagnosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after ILD differential diagnosis