≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Seropositive rheumatoid arthritis, strict definition

DOID EFO MESH SNOMED PheWeb

RHEUMA_SEROPOS_STRICT

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector
diagram bullet

Check conditions

RHEUMA_SEROPOS_OTH_ICD10

8162

diagram downward connector
diagram bullet

Filter registries

KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 M05

7860

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

4024

diagram downward connector

Check minimum number of events None

4024

diagram downward connector

Include endpoints None

4024

diagram downward connector
RHEUMA_SEROPOS_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 4024 2795 1229
Unadjusted prevalence (%) 1.13 1.41 0.78
Mean age at first event (years) 55.49 53.60 59.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.07 [1.47, 2.93] 3.2e-5 349
15 years 0.01 1.57 [1.17, 2.12] 2.8e-3 192
5 years 0.00 2.24 [1.66, 3.02] 1.2e-7 84
1 year 0.00 2.52 [1.49, 4.24] 5.3e-4 17

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: RHEUMA_SEROPOS_STRICT – Seropositive rheumatoid arthritis, strict definition
GWS hits: 8

Survival analyses between endpoints

↥

Plot

before Seropositive rheumatoid arthritis, strict definition
after Seropositive rheumatoid arthritis, strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Seropositive rheumatoid arthritis, strict definition

↥