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Type 1 diabetes, strict definition, subgroup 2

DOID EFO MESH SNOMED PheWeb

T1D_STRICT2

diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not E4_DM2
and not PANCREATITIS
and not INSULIN_INTER_AND_LONG
and KELA_DIAB_INSUL
and INSULIN_SHORTFAST

144

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version

Pre-conditions EVENT_AGE<40

0

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Check minimum number of events None

0

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Include endpoints

110

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T1D_STRICT2

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 110 50 60
Unadjusted prevalence (%) 0.03 0.03 0.04
Mean age at first event (years) 15.83 13.78 17.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: T1D_STRICT2 – Type 1 diabetes, strict definition, subgroup 2
GWS hits:

Survival analyses between endpoints

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Plot

before Type 1 diabetes, strict definition, subgroup 2
after Type 1 diabetes, strict definition, subgroup 2

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Drugs most likely to be purchased after Type 1 diabetes, strict definition, subgroup 2

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