Hypertensive diseases


hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries None


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Check pre-conditions, main-only, mode, ICD version None


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 101714 47923 53791
Unadjusted prevalence (%) 28.59 24.15 34.18
Mean age at first event (years) 57.01 56.72 57.27


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.04 [1.90, 2.19] 8.4e-86 18590
15 years 0.01 1.37 [1.28, 1.47] 2.3e-20 8113
5 years 0.00 2.19 [2.05, 2.33] <1e-100 3996
1 year 0.00 6.37 [5.75, 7.05] <1e-100 2123

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_HYPERTENSION – Hypertensive diseases
GWS hits:

Survival analyses between endpoints


before Hypertensive diseases
after Hypertensive diseases

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Drugs most likely to be purchased after Hypertensive diseases