≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Hypertensive heart and/or renal disease

DOID EFO MESH SNOMED PheWeb

I9_HYPTENSHR

nephrosclerosis: Hardening of the walls of the small arteries and arterioles (small arteries that convey blood from arteries to the even smaller capillaries) of the kidney. This condition is caused by hypertension (high blood pressure)

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 I11, I12, I13
Hospital discharge: ICD-9 4029A|4029B|4039A|4040A
Hospital discharge: ICD-8 40299|40399|40499
Cause of death: ICD-10 I11, I12, I13
Cause of death: ICD-9 4029A|4029B|4039A|4040A
Cause of death: ICD-8 40299|40399|40499

8732

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

8732

diagram downward connector

Check minimum number of events None

8732

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

8732

diagram downward connector
I9_HYPTENSHR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 8732 3373 5359
Unadjusted prevalence (%) 2.45 1.70 3.41
Mean age at first event (years) 66.72 68.41 65.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: I9_HYPTENSHR – Hypertensive heart and/or renal disease
GWS hits:

Survival analyses between endpoints

↥

Plot

before Hypertensive heart and/or renal disease
after Hypertensive heart and/or renal disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertensive heart and/or renal disease

↥